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Synonyms: SH-PTP3, SH-PTP2, SHP2, PTP2C, PTP-1D, NS1, MGC14433, CFC, BPTP3
Anti-PTPN11 Monoclonal Antibody
(8Q534)

| Description | Anti-PTPN11 Monoclonal Antibody (8Q534) is a Mouse antibody targeting PTPN11. Anti-PTPN11 Monoclonal Antibody (8Q534) can be used in IHC,IF,FCM. |
| Synonyms | SH-PTP3, SH-PTP2, SHP2, PTP2C, PTP-1D, NS1, MGC14433, CFC, BPTP3 |
| Ig Type | IgG1 |
| Clone | 8Q534 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PTPN11 (AA: 263-329) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PTPN11 |
| Gene ID | |
| Protein Name | Tyrosine-protein phosphatase non-receptor type 11 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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