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DAMGO (TFA)

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Catalog No. TP1607Cas No. 950492-85-0

DAMGO is a selective peptide agonist of the µ-opioid receptor .

DAMGO (TFA)

DAMGO (TFA)

😃Good
Catalog No. TP1607Cas No. 950492-85-0
DAMGO is a selective peptide agonist of the µ-opioid receptor .
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$42InquiryInquiry
5 mg$72InquiryInquiry
10 mg$130InquiryInquiry
25 mg$279InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
DAMGO is a selective peptide agonist of the µ-opioid receptor .
Chemical Properties
Molecular Weight627.61
FormulaC28H36F3N5O8
Cas No.950492-85-0
SmilesOC(=O)C(F)(F)F.C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO
Relative Density.no data available
SequenceTyr-{d-Ala}-Gly-{Me-Phe}-Gly-ol
Sequence ShortY-{d-Ala}-G-{Me-Phe}-G-ol
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 125 mg/mL (199.17 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.5933 mL7.9667 mL15.9335 mL79.6673 mL
5 mM0.3187 mL1.5933 mL3.1867 mL15.9335 mL
10 mM0.1593 mL0.7967 mL1.5933 mL7.9667 mL
20 mM0.0797 mL0.3983 mL0.7967 mL3.9834 mL
50 mM0.0319 mL0.1593 mL0.3187 mL1.5933 mL
100 mM0.0159 mL0.0797 mL0.1593 mL0.7967 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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