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Anti-NT-proBNP/NPPB Antibody (2S162)
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Catalog No. TMAB-09661
Anti-NT-proBNP/NPPB Antibody (2S162) is a Mouse antibody targeting NT-proBNP/NPPB. Anti-NT-proBNP/NPPB Antibody (2S162) can be used in WB.
Anti-NT-proBNP/NPPB Antibody (2S162)
Anti-NT-proBNP/NPPB Antibody (2S162)
😃Good
Catalog No. TMAB-09661
Anti-NT-proBNP/NPPB Antibody (2S162) is a Mouse antibody targeting NT-proBNP/NPPB. Anti-NT-proBNP/NPPB Antibody (2S162) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,058 | 7-10 days | 7-10 days | |
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-NT-proBNP/NPPB Antibody (2S162) is a Mouse antibody targeting NT-proBNP/NPPB. Anti-NT-proBNP/NPPB Antibody (2S162) can be used in WB. |
| Ig Type | IgG |
| Clone | 2S162 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Brain and also in atria, but at much lower levels than ANP. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume. The 32-amino acid polypeptide BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing. |
| Immunogen | Recombinant Protein: human NT-proBNP protein |
| Antigen Species | Human |
| Gene Name | NPPB |
| Gene ID | |
| Protein Name | Natriuretic peptides B |
| Uniprot ID | |
| Function | Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. |
| Molecular Weight | Theoretical: 8.5/15 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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