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Anti-TPSAB1 Monoclonal Antibody (9M588)
(Synonyms: Tryptase-2, TPSB2, TPSB1, TPS2, TPS1) Copy Product Info
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Synonyms: Tryptase-2, TPSB2, TPSB1, TPS2, TPS1
Catalog No. TMAT-1341 Copy Product Info
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Anti-TPSAB1 Monoclonal Antibody (9M588) is a Mouse antibody targeting TPSAB1. Anti-TPSAB1 Monoclonal Antibody (9M588) can be used in IHC,IF,FCM.
Anti-TPSAB1 Monoclonal Antibody
(9M588)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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| Description | Anti-TPSAB1 Monoclonal Antibody (9M588) is a Mouse antibody targeting TPSAB1. Anti-TPSAB1 Monoclonal Antibody (9M588) can be used in IHC,IF,FCM. |
| Synonyms | Tryptase-2, TPSB2, TPSB1, TPS2, TPS1 |
| Ig Type | IgG1 |
| Clone | 9M588 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TPSAB1 (AA: 31-275) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TPSAB1 |
| Gene ID | |
| Protein Name | Tryptase alpha/beta-1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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