Anti-CD6 Antibody (9H618)

Name: Anti-CD6 Antibody (9H618)
Brand: TargetMol
SKU: TMAY-03424
Rating: 4.5 (1 reviews)

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Catalog No. TMAY-03424

Alias TP120, CD6 molecule

Anti-CD6 Antibody (9H618) is a Rabbit antibody targeting CD6. Anti-CD6 Antibody (9H618) can be used in FCM.

Anti-CD6 Antibody (9H618)

😃Good

Catalog No. TMAY-03424Alias TP120, CD6 molecule

Anti-CD6 Antibody (9H618) is a Rabbit antibody targeting CD6. Anti-CD6 Antibody (9H618) can be used in FCM.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 μL	$270	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Anti-CD6 Antibody (9H618) is a Rabbit antibody targeting CD6. Anti-CD6 Antibody (9H618) can be used in FCM.
Synonyms	TP120, CD6 molecule
Ig Type	Rabbit IgG
Clone	9H618
Reactivity	Mouse
Specificity	Mouse CD6
Verified Activity	Flow cytometric analysis of CD6 expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse CD6, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application	FCM
Recommended Dose	FCM: 1:25-1:100
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD6 / Cluster of Differentiation 6 (rM CD6 / Cluster of Differentiation 6; TMPY-02254; Q91WN5; Met1-Gly396).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	T-cell differentiation antigen CD6, also known as TP12 and CD6, is a single-pass type I membrane protein which contains threeSRCR domains. CD6 / TP12 is a cell surface glycoprotein expressed primarily on T cells, it may function as a costimulatory molecule and may play a role in autoreactive immune responses. CD6 / TP12 is expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. CD6 ligand termed CD166 (previously known as activated leukocyte cell adhesion molecule, ALCAM ) has been identified and shown to be expressed on activated T cells, B cells, thymic epithelium, keratinocytes, and in rheumatoid arthritis synovial tissue. CD6 / TP12 binds to activated leukocyte cell adhesion molecule ( CD166 ), and is considered as a costimulatory molecule involved in lymphocyte activation and thymocyte development. CD6 / TP12 partially associates with the TCR / CD3 complex and colocalizes with it at the center of the mature immunological synapse (IS) on T lymphocytes. During thymic development CD6-dependent signals may contribute both to thymocyte survival, and to the overall functional avidity of selection in both man and mouse.

Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	APC/PerCP/FITC/PE
Antibody Types Available	5

Antigen Details

Immunogen	Recombinant Protein: Mouse CD6 / Cluster of Differentiation 6 Protein (TMPY-02254)
Antigen Species	Mouse
Biology Area	ITIM/ITAM Immunoreceptors and Related Molecules

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc