Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-CD6 Antibody (3M203)

(Synonyms: TP120, CD6 molecule) Copy Product Info
🥰Excellent

Synonyms: TP120, CD6 molecule

Catalog No. TMAY-03813 Copy Product Info
🥰Excellent
Anti-CD6 Antibody (3M203) is a Mouse antibody targeting CD6. Anti-CD6 Antibody (3M203) can be used in FCM.
Anti-CD6 Antibody
(3M203)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-CD6 Antibody (3M203) is a Mouse antibody targeting CD6. Anti-CD6 Antibody (3M203) can be used in FCM.
SynonymsTP120, CD6 molecule
Ig Type
Mouse IgG2a
Clone
3M203
Reactivity
Rat
Specificity
Rat CD6
Application
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD6 / Cluster of Differentiation 6 (rR CD6 / Cluster of Differentiation 6; TMPY-03731; Q812A4; Met1-Asn396). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundT-cell differentiation antigen CD6, also known as TP12 and CD6, is a single-pass type I membrane protein which contains threeSRCR domains. CD6 / TP12 is a cell surface glycoprotein expressed primarily on T cells, it may function as a costimulatory molecule and may play a role in autoreactive immune responses. CD6 / TP12 is expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. CD6 ligand termed CD166 (previously known as activated leukocyte cell adhesion molecule, ALCAM ) has been identified and shown to be expressed on activated T cells, B cells, thymic epithelium, keratinocytes, and in rheumatoid arthritis synovial tissue. CD6 / TP12 binds to activated leukocyte cell adhesion molecule ( CD166 ), and is considered as a costimulatory molecule involved in lymphocyte activation and thymocyte development. CD6 / TP12 partially associates with the TCR / CD3 complex and colocalizes with it at the center of the mature immunological synapse (IS) on T lymphocytes. During thymic development CD6-dependent signals may contribute both to thymocyte survival, and to the overall functional avidity of selection in both man and mouse.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Rat CD6 / Cluster of Differentiation 6 Protein (TMPY-03731)
Antigen Species
Rat
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Calculator

  • Dilution Calculator
  • Reconstitution Calculator

Keywords

Related Tags: