Anti-CD6 Antibody (3M203)

Name: Anti-CD6 Antibody (3M203)
Brand: TargetMol
SKU: TMAY-03813
Rating: 4.5 (1 reviews)

😃Good

Catalog No. TMAY-03813

Alias TP120, CD6 molecule

Anti-CD6 Antibody (3M203) is a Mouse antibody targeting CD6. Anti-CD6 Antibody (3M203) can be used in FCM.

Anti-CD6 Antibody (3M203)

😃Good

Catalog No. TMAY-03813Alias TP120, CD6 molecule

Anti-CD6 Antibody (3M203) is a Mouse antibody targeting CD6. Anti-CD6 Antibody (3M203) can be used in FCM.

Pack Size	Price	Availability	Quantity
100 μL	$198	7-10 days

Bulk & Custom

Add to Cart

Questions

Resource Download

Instruction Manual of Detection Antibody

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Antibody Type: Mouse Monoclonal Application: FCM Reactivity: Rat
Alias	TP120, CD6 molecule
Ig Type	Mouse IgG2a
Clone	3M203
Reactivity	Rat
Verified Activity	Flow cytometric analysis of Rat CD6 expression on SD rat splenocytes. Cells were stained with purified anti-Rat CD6, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application	FCM
Recommended Dose	FCM: 1:25-1:100
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD6 / Cluster of Differentiation 6 (rR CD6 / Cluster of Differentiation 6; TMPY-03731; Q812A4; Met1-Asn396). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	T-cell differentiation antigen CD6, also known as TP12 and CD6, is a single-pass type I membrane protein which contains threeSRCR domains. CD6 / TP12 is a cell surface glycoprotein expressed primarily on T cells, it may function as a costimulatory molecule and may play a role in autoreactive immune responses. CD6 / TP12 is expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. CD6 ligand termed CD166 (previously known as activated leukocyte cell adhesion molecule, ALCAM ) has been identified and shown to be expressed on activated T cells, B cells, thymic epithelium, keratinocytes, and in rheumatoid arthritis synovial tissue. CD6 / TP12 binds to activated leukocyte cell adhesion molecule ( CD166 ), and is considered as a costimulatory molecule involved in lymphocyte activation and thymocyte development. CD6 / TP12 partially associates with the TCR / CD3 complex and colocalizes with it at the center of the mature immunological synapse (IS) on T lymphocytes. During thymic development CD6-dependent signals may contribute both to thymocyte survival, and to the overall functional avidity of selection in both man and mouse.

Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	APC/FITC/PE
Antibody Types Available	4

Antigen Details

Immunogen	Recombinant Protein: Rat CD6 / Cluster of Differentiation 6 Protein (TMPY-03731)
Antigen Species	Rat
Biology Area	ITIM/ITAM Immunoreceptors and Related Molecules

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

Sci Citations

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc