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ELA-11 (human) acetate(1784687-32-6 free base)

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Catalog No. TP1922L1

ELA-11 (human) acetate high affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.

ELA-11 (human) acetate(1784687-32-6 free base)
Other Forms of ELA-11 (human) acetate(1784687-32-6 free base):
ELA-11(human)TP19221784687-32-6
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ELA-11 (human) acetate(1784687-32-6 free base)

🥰Excellent
Purity: 99.53%
Catalog No. TP1922L1
ELA-11 (human) acetate high affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.
Pack SizePriceAvailabilityQuantity
1 mg$133In Stock
5 mg$302In Stock
10 mg$453In Stock
25 mg$748In Stock
50 mg$1,050In Stock
100 mg$1,420In Stock
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Purity:99.53%
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COA MS HPLC

Product Introduction

Bioactivity
Description
ELA-11 (human) acetate high affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.
Targets&IC50
Apelin:Ki = 14 nM
Chemical Properties
Molecular Weight1343.61
FormulaC60H94N16O15S2
SmilesO=C(N1[C@@H](CCC1)C(O)=O)[C@H](CC2=CC=CC=C2)NC([C@H]3N(CCC3)C([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@@H](NC([C@H](CC(C)C)NC([C@H]4N(CCC4)C([C@H](CCSC)NC([C@@H](N)CS)=O)=O)=O)=O)CC5=CN=CN5)=O)=O)=O)=O)=O.CC(O)=O
Relative Density.no data available
ColorWhite
AppearanceSolid
SequenceH-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro-OH
Sequence ShortCMPLHSRVPFP
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mM, Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.7443 mL3.7213 mL7.4426 mL37.2132 mL
5 mM0.1489 mL0.7443 mL1.4885 mL7.4426 mL
10 mM0.0744 mL0.3721 mL0.7443 mL3.7213 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

ELA11 (human) acetate(1784687326 free base)ELA-11 acetate(1784687-32-6 free base)ELA 11 (human) acetate(1784687 32 6 free base)ApelinreceptorApelin receptor
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