20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19374 | INT | Iodonitrotetrazolium chloride,p-Iodonitrotetrazolium Violet | Others |
Iodonitrotetrazolium chloride (INT), serves as the electron acceptor in a range of dehydrogenase colorimetric analyses. | |||
T11662L | INT-777 | S-EMCA | GPCR19 |
INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats... | |||
T9795 | INT. 2 | ||
INT. 2 is a useful organic compound for research related to life sciences. The catalog number is T9795 and the CAS number is 210193-42-3. | |||
T11661 | INT-767 | FXR , GPCR19 | |
INT-767 is a potent farnesoid X receptor (FXR)/TGR5 dual agonist that prevents NASH and promotes visceral adipose brown lipogenesis and mitochondrial function for the study of non-alcoholic steatohepatitis. | |||
T8780 | AMG131 | INT-131,AMG-131,CHS 131 | PPAR |
AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin depende... | |||
T77385 | Idactamab | INT-001 | |
Idactamab (INT-001) is a monoclonal antibody to the human amino acid transport protein ASCT2. | |||
T36792 | DNP-INT | ||
DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM). It inhibits electron flow from water to... | |||
T1789 | Obeticholic Acid | INT-747,6-Ethylchenodeoxycholic acid,6-ECDCA | FXR , Autophagy |
Obeticholic Acid (6-ECDCA) is a Farnesoid X Receptor Agonist. The mechanism of action of obeticholic acid is as a Farnesoid X Receptor Agonist. | |||
T9494 | Imidazole-5-propionic acid | Imidazolylpropionic acid,SALOR-INT L480258-1EA,Deamino-histidine | Dehydrogenase |
Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination. Imidazole-5-propionic acid is potent inhibitors of G. candidum histidinol dehydrogen... | |||
T11662 | INT-777 R-enantiomer | S-EMCA R enantiomer | Others |
INT-777 is the R-enantiomer of INT-777, less potent than INT-777,EC50 of 4.79 μM for TGR5. | |||
T68567 | AMG-131 besylate | ||
AMG-131 besylate is a hypoglycemic agent. It is a potent PPARγ partial agonist that displays robust glucose-lowering activity in rodent models of diabetes while exhibiting a reduced side-effects profile compared to marke... | |||
T19241 | Cloquintocet-mexyl | Others | |
Cloquintocet-mexyl, a herbicide, targets and controls coarse annual grasses within the Poaceae family. | |||
T67152 | Dacomitinib Intermediate 2 | N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine | Others |
Dacomitinib Intermediate 2 (N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine) has anticancer activity and can be used to study lung cancer. | |||
T5636 | Adavivint | Adavivint (SM04690) | Wnt/beta-catenin |
Adavivint (Adavivint (SM04690)) (SM04690) is a Wnt pathway inhibitor. | |||
TP1484L | α2β1 Integrin Ligand Peptide acetate | α2β1 Integrin Ligand Peptide acetate (134580-64-6) | Integrin |
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor. α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the... | |||
T9151 | Teplinovivint | Wnt/beta-catenin | |
Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential utility in tendinopathy research. | |||
T8750 | LX-4211 intermediate | Others | |
LX-4211 intermediate is a synthetic intermediate of LX-4211, a potent SGLT1/2 inhibitor used as an antidiabetic agent. | |||
TQ0007 | Cintirorgon | LYC-55716 | ROR |
Cintirorgon (LYC-55716) is a selective, oral agonist of RORγ. Cintirorgon modulates gene expression of RORγ expressing T lymphocyte immune cells. | |||
T8333 | Aurintricarboxylic acid | ATA,NSC-4056,NSC4056,NSC 4056 | Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase |
Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. | |||
TP1422 | Interleukin (IL)-6 Receptor | Others | |
Interleukin (IL)-6 Receptor is a peptide. |