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Anti-Intrinsic Factor Antibody (8L240) is a Rabbit antibody targeting Intrinsic Factor. Anti-Intrinsic Factor Antibody (8L240) can be used in ELISA,ELISA(Cap).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $93 | 7-10 days | |
100 μL | $269 | 7-10 days |
Description | Anti-Intrinsic Factor Antibody (8L240) is a Rabbit antibody targeting Intrinsic Factor. Anti-Intrinsic Factor Antibody (8L240) can be used in ELISA,ELISA(Cap). |
Alias | TCN3, INF, IFMH, IF, gastric intrinsic factor (vitamin B synthesis) |
Ig Type | Monoclonal Rabbit IgG |
Clone | 8L240 |
Reactivity | Human |
Application | ELISA,ELISA(Cap) |
Recommended Dose | ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Gastric intrinsic factor / GIF (rh Gastric intrinsic factor / GIF; TMPY-03221; P27352-1; Met1-Tyr417). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to gastric intrinsic factor. This new complex travels to the ileum, where special epithelial cells endocytose them. Inside the cell, B12 dissociates once again and binds to another protein, transcobalamin II. The new complex can exit the epithelial cells to enter the liver. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Gastric intrinsic factor / GIF Protein (TMPY-03221) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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