t 6

CD1 proteins are a family of major histocompatibility complex (MHC) class I-like antigen-presenting molecules that present lipids to T cells. The cytoplasmic tails (CTs) of all human CD1 isoforms, with the exception of CD1a, contain tyrosine-based sorting motifs, responsible for the internalization of proteins by the clathrin-mediated pathway. CD1a closer to MHC class I in its trafficking and potential antigen-loading compartments among CD1 isoforms.

Expression system: E. coli
Length: 1-153, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1820-2590, Partial
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 1792-2590, Partial
Activity: Not Tested

Expression system: E. coli
Length: 2-554, Partial
Activity: Not Tested

Expression system: E. coli
Length: 2-558, Full Length of Mature Protein
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 2-558, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 2-95, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 146-384, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1-335, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 24-164, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 22-225, Extracellular Domain
Activity: Not Tested

Expression system: HEK293 Cells
Length: 42-349, Extracellular Domain
Activity: Not Tested

Expression system: HEK293 Cells
Length: 33-320, Extracellular Domain
Activity: BLI、ELISA

SECTM1A (secreted and transmembrane 1A), is 192 amino acid (aa) protein, appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 27 kDa intracellular type I transmembrane protein that shows a perinuclear, Golgi like staining pattern, or as a 20 kDa soluble, secreted form, and is produced by some myeloid cells and by thymic epithelia and fibroblasts. Stimulation with IFN gamma is often necessary to detect human SECTM1 expression, and it is thought to be an interferon early response gene. Mouse SECTM1A cDNA encodes a signal sequence, an extracellular domain with four potential N linked glycosylation sites, a transmembrane sequence, and a very short (approximately 6 aa) cytoplasmic sequence. SECTM1 proteins from human and mouse show species specific binding of CD7 and co stimulation of T cells, including enhancement of CD3 induced proliferation.

Butyrophilin-like 6 (BTNL6) is a member of the BTN MOG Ig-superfamily and functions with BTNL1 as a regulator of immune cell proliferation. The Btnl6 gene is found only in mice. BTNL6 expression is coordinated as a heteromeric protein with BTNL1, and the presence of this complex is correlated with expansion of gamma δ T cells, especially those containing V gamma 7Vδ4 TCR. Btnl6 shows striking sequence similarity to Skint1; is also largely restricted to an epithelial tissue (the small intestine) replete with T cells. Our in-house studies showed BTNL6 co-inhibited anti-CD3 induced IL-2 secretion on CD3+ cells.

Expression system: E. coli
Length: 140-317, Partial
Activity: BLI

Expression system: E. coli
Length: 2-234, Partial
Activity: Not Tested

Expression system: E. coli
Length: 2-338, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-272, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-491, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 30-447, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 22-158, Partial
Activity: BLI、Cells

Expression system: HEK293 Cells
Length: 20-355, Partial
Activity: Not Tested