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Ethyl 4-bromocrotonate

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Catalog No. T66097Cas No. 37746-78-4
Alias (E)-Ethyl 4-bromobut-2-enoate

Ethyl 4-bromocrotonate ((E)-Ethyl 4-bromobut-2-enoate) is an antimicrobial compound belonging to the ester group. As an important pharmaceutical intermediate, it has been used as a substrate for enzyme-catalyzed reactions, and as a tool for studying enzyme kinetics. It has also been found to have anti-inflammatory and analgesic properties.

Ethyl 4-bromocrotonate

Ethyl 4-bromocrotonate

😃Good
Catalog No. T66097Alias (E)-Ethyl 4-bromobut-2-enoateCas No. 37746-78-4
Ethyl 4-bromocrotonate ((E)-Ethyl 4-bromobut-2-enoate) is an antimicrobial compound belonging to the ester group. As an important pharmaceutical intermediate, it has been used as a substrate for enzyme-catalyzed reactions, and as a tool for studying enzyme kinetics. It has also been found to have anti-inflammatory and analgesic properties.
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1 g$34-In Stock
5 g$74-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Ethyl 4-bromocrotonate ((E)-Ethyl 4-bromobut-2-enoate) is an antimicrobial compound belonging to the ester group. As an important pharmaceutical intermediate, it has been used as a substrate for enzyme-catalyzed reactions, and as a tool for studying enzyme kinetics. It has also been found to have anti-inflammatory and analgesic properties.
In vitro
Ethyl 4-bromocrotonate shows antifungal activity for C. albicans, A. niger, M. mucedo, T. mentagrophytes. At PH=7.0 and in presence of 10% beef serum, Ethyl 4-bromocrotonate exhibits MIC of 40 μg/mL, 80 μg/mL, 7 μg/mL, 4 μg/mL for C. albicans, A. niger, M. mucedo, T. mentagrophytes, respectively[1].
Synonyms(E)-Ethyl 4-bromobut-2-enoate
Chemical Properties
Molecular Weight193.04
FormulaC6H9BrO2
Cas No.37746-78-4
SmilesCCOC(=O)\C=C\CBr
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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