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Anti-CD64 Antibody (5T6)
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Catalog No. TMAY-00525
Alias Fc γ RI, Fc receptor, IgG, high affinity I, Fc gamma RI, CD64
Anti-CD64 Antibody (5T6) is a Rabbit antibody targeting CD64. Anti-CD64 Antibody (5T6) can be used in ELISA,FCM.
Anti-CD64 Antibody (5T6)
Anti-CD64 Antibody (5T6)
😃Good
Catalog No. TMAY-00525Alias Fc γ RI, Fc receptor, IgG, high affinity I, Fc gamma RI, CD64
Anti-CD64 Antibody (5T6) is a Rabbit antibody targeting CD64. Anti-CD64 Antibody (5T6) can be used in ELISA,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD64 Antibody (5T6) is a Rabbit antibody targeting CD64. Anti-CD64 Antibody (5T6) can be used in ELISA,FCM. |
| Alias | Fc γ RI, Fc receptor, IgG, high affinity I, Fc gamma RI, CD64 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 5T6 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD64 expression on human whole blood monocytes. Cells were stained with purified anti-Human CD64, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | ELISA,FCM |
| Recommended Dose | ELISA: 1:5000-1:10000; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD64 / FCGR1 (rh CD64 / FCGR1; TMPY-04261; NP_000557.1; Met1-Pro288). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membraneglycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of asignal peptidethat allows its transport to the surface of a cell, threeextracellularimmunoglobulin domainsof the C2-type that it uses to bind antibody, a hydrophobictransmembrane domain, and a short cytoplasmic tail. CD64 isconstitutivelyfound on only macrophages and monocytes, but treatment of polymorphonuclear leukocyteswith cytokines likeIFNγandG-CSFcan induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses. |
| Conjucates | Unconjugated |
| Others Formats | FITC |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human CD64 / FCGR1 Protein (TMPY-04261) |
| Antigen Species | Human |
| Biology Area | Fc Receptors |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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