Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML-SA5 is an MCOLN1 agonist and arrests autophagic flux by perturbing fusion between autophagosomes and lysosomes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 33.00 | |
5 mg | In stock | $ 76.00 | |
10 mg | In stock | $ 133.00 | |
25 mg | In stock | $ 283.00 | |
50 mg | In stock | $ 455.00 | |
100 mg | In stock | $ 672.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 77.00 |
Description | ML-SA5 is an MCOLN1 agonist and arrests autophagic flux by perturbing fusion between autophagosomes and lysosomes. |
In vitro | Activating MCOLN1 with ML-SA5 triggers cell death of a number of cancer cells by evoking autophagic arrest and subsequent apoptotic response and cell cycle arrest, with little or no effect observed on normal cells[1]. |
In vivo | ML-SA5 in Patu 8988 t xenograft mice profoundly suppresses tumor growth and improves survival[1]. |
Molecular Weight | 457.99 |
Formula | C19H24ClN3O4S2 |
CAS No. | 2418670-70-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (109.17 mM)
You can also refer to dose conversion for different animals. More
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ML-SA5 2418670-70-7 Autophagy MLSA5 ML SA5 inhibitor inhibit