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Tabernanthalog

Name: Tabernanthalog
Brand: TargetMol
SKU: T60221
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60221Cas No. 2483829-58-7

Alias TBG

Tabernanthalog (TBG) is a 5-HT2A agonist. In rodents,Tabernanthalog has been found to promote structural neuroplasticity, reduce alcohol-seeking and heroin-seeking behavior, and produce antidepressant effects.

Tabernanthalog

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Purity: 99.89%

Catalog No. T60221Alias TBGCas No. 2483829-58-7

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$195	In Stock	In Stock
2 mg	$293	In Stock	In Stock
5 mg	$448	In Stock	In Stock
10 mg	$658	In Stock	In Stock
25 mg	$987	In Stock	In Stock
50 mg	$1,380	-	In Stock
100 mg	$1,890	-	In Stock
500 mg	$3,780	-	In Stock
1 mL x 10 mM (in DMSO)	$383	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.89%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Tabernanthalog (TBG) is a 5-HT2A agonist. In rodents,Tabernanthalog has been found to promote structural neuroplasticity, reduce alcohol-seeking and heroin-seeking behavior, and produce antidepressant effects.
In vivo	After 7 days of unpredictable mild stress (UMS) in mice, immobility time was significantly increased after UMS. This effect was rescued by a 50 mg/kg, but not 10 mg/kg, dose of Tabernanthalog.
Synonyms	TBG

Chemical Properties

Molecular Weight	230.31
Formula	C₁₄H₁₈N₂O
Cas No.	2483829-58-7
Smiles	O(C)C=1C=C2C(C3=C(N2)CCN(C)CC3)=CC1
Relative Density.	1.143 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (434.2 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3420 mL	21.7099 mL	43.4197 mL	217.0987 mL
5 mM	0.8684 mL	4.3420 mL	8.6839 mL	43.4197 mL
10 mM	0.4342 mL	2.1710 mL	4.3420 mL	21.7099 mL
20 mM	0.2171 mL	1.0855 mL	2.1710 mL	10.8549 mL
50 mM	0.0868 mL	0.4342 mL	0.8684 mL	4.3420 mL
100 mM	0.0434 mL	0.2171 mL	0.4342 mL	2.1710 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc