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Gevotroline

Name: Gevotroline
Brand: TargetMol
SKU: T68080
Price: 90 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T68080Cas No. 107266-06-8

Gevotroline, a chemical in palm wine that can be used to treat psychosis, is a 5-HT2 receptor antagonist that can be used to study behavioral disorders.

Gevotroline

🥰Excellent

Purity: 98.65%

Catalog No. T68080Cas No. 107266-06-8

Gevotroline, a chemical in palm wine that can be used to treat psychosis, is a 5-HT2 receptor antagonist that can be used to study behavioral disorders.

Pack Size	Price	Availability
1 mg	$90	In Stock
5 mg	$210	In Stock
10 mg	$310	In Stock
25 mg	$586	In Stock
50 mg	$790	In Stock
100 mg	$1,080	In Stock
500 mg	$2,190	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.65%

Resource Download

COA FNMR HNMR LCMS

Product Introduction

Bioactivity

Description	Gevotroline, a chemical in palm wine that can be used to treat psychosis, is a 5-HT2 receptor antagonist that can be used to study behavioral disorders.
In vivo	During the acrophase (peak) of the effects of the circadian rhythm on the hypothalamic-pituitary-adrenal axis, the ED50 was 9.6 mmol/kg for gevotroline.[1]

Chemical Properties

Molecular Weight	309.38
Formula	C₁₉H₂₀FN₃
Cas No.	107266-06-8
Smiles	C(CCC=1C=CC=NC1)N2CC=3C=4C(NC3CC2)=CC=C(F)C4

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (177.77 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2323 mL	16.1614 mL	32.3227 mL	161.6135 mL
5 mM	0.6465 mL	3.2323 mL	6.4645 mL	32.3227 mL
10 mM	0.3232 mL	1.6161 mL	3.2323 mL	16.1614 mL
20 mM	0.1616 mL	0.8081 mL	1.6161 mL	8.0807 mL
50 mM	0.0646 mL	0.3232 mL	0.6465 mL	3.2323 mL
100 mM	0.0323 mL	0.1616 mL	0.3232 mL	1.6161 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc