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TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

(-)-GSK598809 hydrochloride

🥰Excellent
Catalog No. T67913Cas No. 863766-31-8

(-)-GSK598809 hydrochloride is the isomer of GSK598809. GSK598809 is a selective antagonist of the dopamine D3 receptor (DRD3), which is a neural response that selectively enhances reward anticipation in drug and alcohol dependence during monetary policy and may repair reward deficits in substance dependence.

(-)-GSK598809 hydrochloride
Other Forms of (-)-GSK598809 hydrochloride:

(-)-GSK598809 hydrochloride

🥰Excellent
Purity: 97.66%
Catalog No. T67913Cas No. 863766-31-8
(-)-GSK598809 hydrochloride is the isomer of GSK598809. GSK598809 is a selective antagonist of the dopamine D3 receptor (DRD3), which is a neural response that selectively enhances reward anticipation in drug and alcohol dependence during monetary policy and may repair reward deficits in substance dependence.
Pack SizePriceAvailabilityQuantity
2 mg$39In Stock
5 mg$66In Stock
10 mg$100In Stock
25 mg$167In Stock
50 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$75In Stock
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Batch Information

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Purity:97.66%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
(-)-GSK598809 hydrochloride is the isomer of GSK598809. GSK598809 is a selective antagonist of the dopamine D3 receptor (DRD3), which is a neural response that selectively enhances reward anticipation in drug and alcohol dependence during monetary policy and may repair reward deficits in substance dependence.
Chemical Properties
Molecular Weight517.97
FormulaC22H24ClF4N5OS
Cas No.863766-31-8
SmilesFC1=C([C@@]23[C@@](C2)(CN(CCCSC=4N(C)C(=NN4)C5=C(C)N=CO5)C3)[H])C=CC(C(F)(F)F)=C1.Cl
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (115.84 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9306 mL9.6531 mL19.3061 mL96.5307 mL
5 mM0.3861 mL1.9306 mL3.8612 mL19.3061 mL
10 mM0.1931 mL0.9653 mL1.9306 mL9.6531 mL
20 mM0.0965 mL0.4827 mL0.9653 mL4.8265 mL
50 mM0.0386 mL0.1931 mL0.3861 mL1.9306 mL
100 mM0.0193 mL0.0965 mL0.1931 mL0.9653 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

GSK-598809 HydrochlorideGSK598809 HydrochlorideGSK 598809 HydrochlorideDopamineReceptorDopamine ReceptorD3 receptor(1S,5R)-GSK598809 hydrochloride
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