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Virodhamine

Name: Virodhamine
Brand: TargetMol
SKU: T64371
Rating: 4.5 (1 reviews)

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Catalog No. T64371Cas No. 287937-12-6

Alias O-arachidonoyl ethanolamine

Virodhamine (O-arachidonoyl ethanolamine), an endocannabinoid, is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine can be used for the research of neurological disorders such as Alzheimer's diseases.

Virodhamine

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Catalog No. T64371Alias O-arachidonoyl ethanolamineCas No. 287937-12-6

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
2 mg	$48	5 days	5 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Virodhamine (O-arachidonoyl ethanolamine), an endocannabinoid, is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine can be used for the research of neurological disorders such as Alzheimer's diseases.
In vitro	virodhamine (50nM, 72h) treatment augmented features associated with megakaryocytic development: cells increased adherence and membrane expansion. virodhamine (10, 20, 40 µM, 72h) treatment increases the expression of CD61[1].
In vivo	Virodhamine (1, 5, 10 mg/kg; i.p. once) repairs the nicotine (0.8 mg/kg) and immobilization stress induced anxiety in Male ICR mice[2].
Synonyms	O-arachidonoyl ethanolamine

Chemical Properties

Molecular Weight	347.53
Formula	C₂₂H₃₇NO₂
Cas No.	287937-12-6
Relative Density.	0.930 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (258.97 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8774 mL	14.3872 mL	28.7745 mL	143.8725 mL
5 mM	0.5755 mL	2.8774 mL	5.7549 mL	28.7745 mL
10 mM	0.2877 mL	1.4387 mL	2.8774 mL	14.3872 mL
20 mM	0.1439 mL	0.7194 mL	1.4387 mL	7.1936 mL
50 mM	0.0575 mL	0.2877 mL	0.5755 mL	2.8774 mL
100 mM	0.0288 mL	0.1439 mL	0.2877 mL	1.4387 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc