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Virodhamine

Name: Virodhamine
Brand: TargetMol
SKU: T64371
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T64371Cas No. 287937-12-6

Alias O-arachidonoyl ethanolamine

Virodhamine (O-arachidonoyl ethanolamine), an endocannabinoid, is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine can be used for the research of neurological disorders such as Alzheimer's diseases.

Virodhamine

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Purity: 98.20%

Catalog No. T64371Alias O-arachidonoyl ethanolamineCas No. 287937-12-6

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
2 mg	$48	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.20%

Appearance:Liquid

Color:Brown

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Virodhamine (O-arachidonoyl ethanolamine), an endocannabinoid, is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine can be used for the research of neurological disorders such as Alzheimer's diseases.
In vitro	virodhamine (50nM, 72h) treatment augmented features associated with megakaryocytic development: cells increased adherence and membrane expansion. virodhamine (10, 20, 40 µM, 72h) treatment increases the expression of CD61[1].
In vivo	Virodhamine (1, 5, 10 mg/kg; i.p. once) repairs the nicotine (0.8 mg/kg) and immobilization stress induced anxiety in Male ICR mice[2].
Synonyms	O-arachidonoyl ethanolamine

Chemical Properties

Molecular Weight	347.53
Formula	C₂₂H₃₇NO₂
Cas No.	287937-12-6
Smiles	CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCCN
Relative Density.	0.930 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (258.97 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8774 mL	14.3872 mL	28.7745 mL	143.8725 mL
5 mM	0.5755 mL	2.8774 mL	5.7549 mL	28.7745 mL
10 mM	0.2877 mL	1.4387 mL	2.8774 mL	14.3872 mL
20 mM	0.1439 mL	0.7194 mL	1.4387 mL	7.1936 mL
50 mM	0.0575 mL	0.2877 mL	0.5755 mL	2.8774 mL
100 mM	0.0288 mL	0.1439 mL	0.2877 mL	1.4387 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc