Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WIN 54954 is a potent, orally active, broad-spectrum antipicornavirus agent with demonstrated efficacy against human rhinovirus, echovirus 9, and enterovirus infections [1] [2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 52.00 | |
5 mg | In stock | $ 123.00 | |
10 mg | In stock | $ 198.00 | |
25 mg | In stock | $ 372.00 | |
50 mg | In stock | $ 619.00 | |
100 mg | In stock | $ 1,090.00 | |
500 mg | In stock | $ 2,230.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 135.00 |
Description | WIN 54954 is a potent, orally active, broad-spectrum antipicornavirus agent with demonstrated efficacy against human rhinovirus, echovirus 9, and enterovirus infections [1] [2]. |
In vitro | WIN 54954 effectively reduces plaque formation in 50 out of 52 rhinovirus serotypes, with minimum inhibitory concentrations (MICs) ranging between 0.007 to 2.2 μg/mL [1]. Additionally, it inhibits 15 commonly isolated enteroviruses, achieving an 80% effective concentration (EC80) at 0.06 μg/mL [1]. |
In vivo | WIN 54954, administered orally at dosages ranging from 2 to 100 mg/kg, effectively prevents paralysis in 50% of mice infected with coxsackievirus A-9 and echovirus-9, with the specific effective doses being 2 mg/kg and 100 mg/kg for each virus, respectively [1]. |
Molecular Weight | 383.27 |
Formula | C18H20Cl2N2O3 |
CAS No. | 107355-45-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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WIN 54954 107355-45-3 inhibitor inhibit