Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CST626 (Compound 9), a pan-IAP degrader PROTAC, effectively degrades XIAP, cIAP1, and cIAP2 in MM.1S cells with DC50 values of 0.7, 2.4, and 6.2 nM, respectively [1].
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Description | CST626 (Compound 9), a pan-IAP degrader PROTAC, effectively degrades XIAP, cIAP1, and cIAP2 in MM.1S cells with DC50 values of 0.7, 2.4, and 6.2 nM, respectively [1]. |
In vitro | CST626 (Compound 9) induces the degradation of cIAP1, cIAP2, and XIAP in a dose-dependent manner with DC50 values of 2.4 nM, 6.2 nM, and 0.7 nM, respectively [1]. CST626 (0-10 μM; 96 h) significantly inhibits the viability of cancer cells [1]. |
Molecular Weight | 1103.42 |
Formula | C61H82N8O9S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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CST626 PROTAC PROTACs inhibitor inhibit