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Anti-LILRA3/CD85e Antibody (2I935)

😃Good
Catalog No. TMAY-02601
Alias LIR-4, LIR4, leukocyte immunoglobulin like receptor A3, ILT-6, ILT6, HM43, HM31, CD85e

Anti-LILRA3/CD85e Antibody (2I935) is a Rabbit antibody targeting LILRA3/CD85e. Anti-LILRA3/CD85e Antibody (2I935) can be used in FCM.

Anti-LILRA3/CD85e Antibody (2I935)

Anti-LILRA3/CD85e Antibody (2I935)

😃Good
Catalog No. TMAY-02601Alias LIR-4, LIR4, leukocyte immunoglobulin like receptor A3, ILT-6, ILT6, HM43, HM31, CD85e
Anti-LILRA3/CD85e Antibody (2I935) is a Rabbit antibody targeting LILRA3/CD85e. Anti-LILRA3/CD85e Antibody (2I935) can be used in FCM.
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100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Anti-LILRA3/CD85e Antibody (2I935) is a Rabbit antibody targeting LILRA3/CD85e. Anti-LILRA3/CD85e Antibody (2I935) can be used in FCM.
AliasLIR-4, LIR4, leukocyte immunoglobulin like receptor A3, ILT-6, ILT6, HM43, HM31, CD85e
Ig Type
Monoclonal Rabbit IgG
Clone
2I935
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human LILRA3(CD85e) expression on human whole blood monocytes. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human LILRA3(CD85e), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human LILRA3/CD85e/ILT6 (rh LILRA3/CD85e/ILT6; TMPY-03696; AAH28208.1; Met1-Glu439).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundILT6, also known as LILRA3, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
FITC/PE
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Human LILRA3/CD85e/ILT6 Protein (TMPY-03696)
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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