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Anti-LILRA3/CD85e Antibody (2I935)
😃Good
Catalog No. TMAY-02601
Alias LIR-4, LIR4, leukocyte immunoglobulin like receptor A3, ILT-6, ILT6, HM43, HM31, CD85e
Anti-LILRA3/CD85e Antibody (2I935) is a Rabbit antibody targeting LILRA3/CD85e. Anti-LILRA3/CD85e Antibody (2I935) can be used in FCM.
Anti-LILRA3/CD85e Antibody (2I935)
Anti-LILRA3/CD85e Antibody (2I935)
😃Good
Catalog No. TMAY-02601Alias LIR-4, LIR4, leukocyte immunoglobulin like receptor A3, ILT-6, ILT6, HM43, HM31, CD85e
Anti-LILRA3/CD85e Antibody (2I935) is a Rabbit antibody targeting LILRA3/CD85e. Anti-LILRA3/CD85e Antibody (2I935) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: FCM Reactivity: Human |
| Alias | LIR-4, LIR4, leukocyte immunoglobulin like receptor A3, ILT-6, ILT6, HM43, HM31, CD85e |
| Ig Type | Rabbit IgG |
| Clone | 2I935 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human LILRA3(CD85e) expression on human whole blood monocytes. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human LILRA3(CD85e), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human LILRA3/CD85e/ILT6 (rh LILRA3/CD85e/ILT6; TMPY-03696; AAH28208.1; Met1-Glu439). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ILT6, also known as LILRA3, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease. |
| Conjucates | Unconjugated |
| Others Formats | FITC/PE |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Protein: Human LILRA3/CD85e/ILT6 Protein (TMPY-03696) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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