store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tegaserod is an orally available 5-HT4R agonist and 5-HT2B receptor antagonist with inhibitory effects on various 5-hydroxytryptamine receptors. Tegaserod has antitumor activity and is used in the treatment of irritable bowel syndrome (IBS).
Pack Size | Availability | Price/USD | Quantity |
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2 mg | In stock | $ 31.00 |
Description | Tegaserod is an orally available 5-HT4R agonist and 5-HT2B receptor antagonist with inhibitory effects on various 5-hydroxytryptamine receptors. Tegaserod has antitumor activity and is used in the treatment of irritable bowel syndrome (IBS). |
In vitro | Tegaserod ( 3,5 μM; 24,48,72 h ) increased the apoptosis of A375, RPMI-7951 ( RPMI ), SH4, B16F10, MeWo and MEL-JUSO cell lines in a time- and dose-dependent manner[1]. |
In vivo | After subcutaneous injection of B16F10 cells in C57BL / 6J mice, tegaserod ( 5 mg / kg ; 1 times a day for 5 consecutive days ) significantly reduced tumor growth, and only a slight decrease in body weight was observed after treatment[1]. |
Molecular Weight | 301.39 |
Formula | C16H23N5O |
CAS No. | 145158-71-0 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (99.54 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Tegaserod 145158-71-0 GPCR/G Protein Neuroscience 5-HT Receptor inhibitor inhibit