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δ7-δ8

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
AY 9944
T14362366-93-8In house
AY 9944 is a specific cholesterol biosynthesis inhibitor that targets the 7-dehydrocholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 also inhibits sterol Δ7-Δ8 isomerase in cultured embryos, leading to the accumulation of cholest-8-en-3β-ol[1][2][3]. Additionally, AY 9944 causes hypocholesterolemia and accumulation of 7DHC.
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4-6 weeks
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Spiroxamine
T36940118134-30-8
Spiroxamine is a tertiary amine fungicide and an inhibitor of δ14 reductase and δ8→δ7 isomerase. Spiroxamine inhibits the growth of N. parvum, B. dothidea, D. seriata, and L. theobromae isolates from grape vines.
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