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AXC-666

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Catalog No. T87874Cas No. 313350-30-0
Alias AXC666

AXC-666 is a TLR agonist and an immuno agonist that can be used to synthesize antibody drug couplers (ADCs).

AXC-666

AXC-666

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Purity: 99.03%
Catalog No. T87874Alias AXC666Cas No. 313350-30-0
AXC-666 is a TLR agonist and an immuno agonist that can be used to synthesize antibody drug couplers (ADCs).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$30In StockIn Stock
5 mg$66In StockIn Stock
10 mg$108In StockIn Stock
25 mg$216In StockIn Stock
50 mg$350In StockIn Stock
100 mg$525-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.03%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
AXC-666 is a TLR agonist and an immuno agonist that can be used to synthesize antibody drug couplers (ADCs).
SynonymsAXC666
Chemical Properties
Molecular Weight283.37
FormulaC16H21N5
Cas No.313350-30-0
SmilesN1=C(N)C=2N=C(N(C2C=3C=CC=CC13)CCCCN)CC
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 40 mg/mL(141.16 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5290 mL17.6448 mL35.2896 mL176.4478 mL
5 mM0.7058 mL3.5290 mL7.0579 mL35.2896 mL
10 mM0.3529 mL1.7645 mL3.5290 mL17.6448 mL
20 mM0.1764 mL0.8822 mL1.7645 mL8.8224 mL
50 mM0.0706 mL0.3529 mL0.7058 mL3.5290 mL
100 mM0.0353 mL0.1764 mL0.3529 mL1.7645 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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