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Anti-ISG15 Antibody-Biotin (8I780)
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Catalog No. TMAY-02414B
Alias UCRP, ISG15 ubiquitin-like modifier, IP17, IMD38, IFI15, hUCRP, G1P2
Anti-ISG15 Antibody-Biotin (8I780) is a Biotin-conjugated Rabbit antibody targeting ISG15. Anti-ISG15 Antibody-Biotin (8I780) can be used in ELISA.
Anti-ISG15 Antibody-Biotin (8I780)
Anti-ISG15 Antibody-Biotin (8I780)
😃Good
Catalog No. TMAY-02414BAlias UCRP, ISG15 ubiquitin-like modifier, IP17, IMD38, IFI15, hUCRP, G1P2
Anti-ISG15 Antibody-Biotin (8I780) is a Biotin-conjugated Rabbit antibody targeting ISG15. Anti-ISG15 Antibody-Biotin (8I780) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | 279 € | 7-10 days |
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Chemical Properties
| Description | Anti-ISG15 Antibody-Biotin (8I780) is a Biotin-conjugated Rabbit antibody targeting ISG15. Anti-ISG15 Antibody-Biotin (8I780) can be used in ELISA. |
| Alias | UCRP, ISG15 ubiquitin-like modifier, IP17, IMD38, IFI15, hUCRP, G1P2 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 8I780 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 0.1-1 μg/mL |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ISG15 (rh ISG15; TMPY-02348; AAH09507.1; Met1-Ser165) and then biotinylated.. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interferon-induced 17 kDa protein (ISG15), a 15-kDa protein of unique primary amino acid sequence, functions intracellularly as a ubiquitin homolog and a cytokine that induces production of IFN-gamma and augments NK / lymphokine-activated killer cell proliferation and function. ISG15 is secreted from monocytes and lymphocytes. ISG15 is a ubiquitin-like molecule that is strongly upregulated by type I interferons as a primary response to diverse microbial and cellular stress stimuli. Alterations in the ISG15 signaling pathway have also been found in several human tumor entities. In addition to being stimulated by type I interferon, expression of ISG15 is greatly induced by viral or bacterial infection through the Janus kinase/signal transducer and activator of transcription (Jak / STAT) signaling pathway. After induction, ISG15 is secreted by monocytes, B- and T-lymphocytes, and fibroblasts. We demonstrate the novel way in which the function of the ISG15 protein is inhibited by influenza B virus, which strongly induces the ISG15 protein: a specific region of the influenza B virus NS1 protein, which includes part of its effector domain, blocks the covalent linkage of ISG15 to its target proteins both in vitro and in infected cells. |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human ISG15 protein (TMPY-02348) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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