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Nesvacumab

(Synonyms: SAR-307746, SAR307746, REGN-910, REGN910) Copy Product Info
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Synonyms: SAR-307746, SAR307746, REGN-910, REGN910

Catalog No. T78248 Copy Product Info
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Nesvacumab (REGN910) is a fully human monoclonal antibody against angiopoietin-2 (Ang2). Nesvacumab inhibits tumor angiogenesis and growth by targeting and neutralizing angiopoietin-2 (Ang2). Nesvacumab is being studied for the treatment of advanced solid tumors.
Nesvacumab
Cas No. 1296818-77-3
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$183-In Stock
5 mg$397-In Stock
10 mg$655-In Stock
25 mg$987-In Stock
50 mg$1,360-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.11% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Nesvacumab (REGN910) is a fully human monoclonal antibody against angiopoietin-2 (Ang2). Nesvacumab inhibits tumor angiogenesis and growth by targeting and neutralizing angiopoietin-2 (Ang2). Nesvacumab is being studied for the treatment of advanced solid tumors.
In vitro
Nesvacumab selectively binds to the Tie2 receptor ligand Angiopoietin-2 (Ang2) and exhibits high affinity (24pM). [1]
SynonymsSAR-307746, SAR307746, REGN-910, REGN910
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetANGPT2
Chemical Properties
Molecular Weight144.84 kDa
Cas No.1296818-77-3
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Related Tags: Nesvacumab chemical structure | Nesvacumab in vitro | Nesvacumab molecular weight