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JNJ-39220675

Name: JNJ-39220675
Brand: TargetMol
SKU: T27678
Price: 293 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T27678Cas No. 959740-39-7

Alias JNJ39220675, JNJ 39220675

JNJ-39220675 (JNJ 39220675) is a selective and brain permeable histamine H3 receptor antagonist.

JNJ-39220675

🥰Excellent

Purity: 99.89%

Catalog No. T27678Alias JNJ39220675, JNJ 39220675Cas No. 959740-39-7

JNJ-39220675 (JNJ 39220675) is a selective and brain permeable histamine H3 receptor antagonist.

Pack Size	Price	Availability
1 mg	$293	In Stock
5 mg	$722	In Stock
10 mg	$987	In Stock
25 mg	$1,520	In Stock
50 mg	$1,980	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.89%

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COA FNMR HNMR LCMS

Product Introduction

Bioactivity

Description	JNJ-39220675 (JNJ 39220675) is a selective and brain permeable histamine H3 receptor antagonist.
In vivo	After establishing a reliable baseline of alcohol and water intake, systemic (subcutaneous) administration of three doses of JNJ 39220675 (0.3, 3, and 10 mg/kg) to rats in the morning (10:00 AM) significantly and dose-dependently reduced alcohol self-administration without altering saccharin self-administration in alcohol-independent rats.
Synonyms	JNJ39220675, JNJ 39220675

Chemical Properties

Molecular Weight	369.43
Formula	C₂₁H₂₄FN₃O₂
Cas No.	959740-39-7
Smiles	O=C(C1=CN=C(OC2=CC=C(F)C=C2)C=C1)N3CCN(CCC3)C4CCC4
Relative Density.	no data available
Color	White
Appearance	Oil

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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