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Amlitelimab (Synonyms: SAR445229, SAR 445229, KY1005, KY 1005)
Catalog No. T78299 Copy Product Info
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Amlitelimab (KY1005) is a monoclonal antibody targeting OX40 ligand (OX40L), inhibiting KLH-driven immune responses, used in the study of atopic dermatitis.
Amlitelimab
Copy Product Info🥰Excellent
Catalog No. T78299
Synonyms SAR445229, SAR 445229, KY1005, KY 1005
Amlitelimab (KY1005) is a monoclonal antibody targeting OX40 ligand (OX40L), inhibiting KLH-driven immune responses, used in the study of atopic dermatitis.
Amlitelimab
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $197 | In Stock | In Stock | |
| 5 mg | $516 | In Stock | In Stock | |
| 10 mg | $828 | - | In Stock | |
| 25 mg | $1,230 | - | In Stock | |
| 50 mg | $1,650 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.41% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Amlitelimab (KY1005) is a monoclonal antibody targeting OX40 ligand (OX40L), inhibiting KLH-driven immune responses, used in the study of atopic dermatitis. |
| In vitro | Amlitelimab (150 μg/mL) effectively inhibits the proliferation of human CD3 T cells [3]. |
| In vivo | In non-human primate graft-versus-host disease (GVHD) models, treatment with Amlitelimab (10mg/kg) showed significant biological activity (extending median GVHD free survival from 8 days to 19.5 days). [1] |
| Synonyms | SAR445229, SAR 445229, KY1005, KY 1005 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFSF4/OX40L/CD252 |
| Molecular Weight | 145.98 kDa |
| Isotype | Human IgG4SP-Opti-LE kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature | Shipping with blue ice/Shipping at ambient temperature. |
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