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Amlitelimab

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Catalog No. T78299
Alias SAR445229, SAR 445229, KY1005, KY 1005

Amlitelimab (KY1005) is a monoclonal antibody targeting OX40 ligand (OX40L), inhibiting KLH-driven immune responses, used in the study of atopic dermatitis.

Amlitelimab

Amlitelimab

😃Good
Catalog No. T78299Alias SAR445229, SAR 445229, KY1005, KY 1005
Amlitelimab (KY1005) is a monoclonal antibody targeting OX40 ligand (OX40L), inhibiting KLH-driven immune responses, used in the study of atopic dermatitis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$197In StockIn Stock
5 mg$516In StockIn Stock
10 mg$828-In Stock
25 mg$1,230-In Stock
50 mg$1,650-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.41% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
Amlitelimab (KY1005) is a monoclonal antibody targeting OX40 ligand (OX40L), inhibiting KLH-driven immune responses, used in the study of atopic dermatitis.
In vitro
Amlitelimab (150 μg/mL) effectively inhibits the proliferation of human CD3 T cells [3].
In vivo
In non-human primate graft-versus-host disease (GVHD) models, treatment with Amlitelimab (10mg/kg) showed significant biological activity (extending median GVHD free survival from 8 days to 19.5 days). [1]
SynonymsSAR445229, SAR 445229, KY1005, KY 1005
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTNFSF4/OX40L/CD252
Chemical Properties
Molecular Weight145.98 kDa
Antibody Information
IsotypeHuman IgG4SP-Opti-LE kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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