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Anti-UBE2L6 Antibody (3D788)

😃Good
Catalog No. TMAY-02404
Alias ubiquitin-conjugating enzyme E2L 6, UBCH8, RIG-B

Anti-UBE2L6 Antibody (3D788) is a Rabbit antibody targeting UBE2L6. Anti-UBE2L6 Antibody (3D788) can be used in ELISA.

Anti-UBE2L6 Antibody (3D788)

Anti-UBE2L6 Antibody (3D788)

😃Good
Catalog No. TMAY-02404Alias ubiquitin-conjugating enzyme E2L 6, UBCH8, RIG-B
Anti-UBE2L6 Antibody (3D788) is a Rabbit antibody targeting UBE2L6. Anti-UBE2L6 Antibody (3D788) can be used in ELISA.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Monoclonal

Application: ELISA

Reactivity: Human
Aliasubiquitin-conjugating enzyme E2L 6, UBCH8, RIG-B
Ig Type
Rabbit IgG
Clone
3D788
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human UBCH8 / UBE2L6 (rh UBCH8 / UBE2L6; TMPY-02842; O14933-1; Met1-Ser153).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundUBCH8, also known as UBE2L6, belongs to the ubiquitin-conjugating enzyme family. The family of ubiquitin-conjugating (E2) enzymes is characterized by the presence of a highly conserved ubiquitin-conjugating (UBC) domain. These domains accommodate the ATP-activated ubiquitin (Ub) or ubiquitin-like (UBL) protein via a covalently linked thioester onto its active-site residue. E2 enzymes act via selective protein-protein interactions with the E1 and E3 enzymes and connect activation to covalent modification. By doing so, E2s differentiate effects on downstream substrates, either with a single Ub/UBL molecule or as a chain. UBCH8 is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. It catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. UBCH8 functions in the E6/E6-AP-induced ubiquitination of p53/TP53 and promotes ubiquitination and subsequent proteasomal degradation of FLT3. At protein level, it is present in natural killer cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human UBCH8 / UBE2L6 protein (TMPY-02842)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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