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Motavizumab
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Catalog No. T76752Cas No. 677010-34-3
Alias MEDI-524, MEDI524
Motavizumab (MEDI-524) is a monoclonal antibody neutralizing respiratory syncytial virus (RSV), altering local and systemic cytokine responses in mouse models, used in the study of RSV infection.
Motavizumab
Motavizumab
Copy Product Info😃Good
Catalog No. T76752Alias MEDI-524, MEDI524Cas No. 677010-34-3
Motavizumab (MEDI-524) is a monoclonal antibody neutralizing respiratory syncytial virus (RSV), altering local and systemic cytokine responses in mouse models, used in the study of RSV infection.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | In Stock | In Stock | |
| 5 mg | $579 | In Stock | In Stock | |
| 10 mg | $892 | - | In Stock | |
| 25 mg | $1,350 | - | In Stock | |
| 50 mg | $1,820 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.17% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Motavizumab (MEDI-524) is a monoclonal antibody neutralizing respiratory syncytial virus (RSV), altering local and systemic cytokine responses in mouse models, used in the study of RSV infection. |
| Targets&IC50 | IgG1:0.07823 nM (EC50), mIgA2:0.2976 nM(EC50), mIgA1:0.1986 nM (EC50) |
| In vivo | In a mouse model, prophylactic administration of Motavizumab (1.25 mg/ mouse) significantly reduced respiratory syncytial virus (RSV) replication, local and systemic cytokine responses, especially TNF-α, IL-1α, IL-12p70, KC, IL-10, and INF-γ. And completely prevented the development of clinically acute RSV disease. [1] |
| Synonyms | MEDI-524, MEDI524 |
| Reactivity | Virus |
| Verified Activity | Immobilized Human RSV post-F Protein (His) at 2 μg/mL can bind Motavizumab. The EC50 is 0.004796 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | RSV-F |
| Molecular Weight | 145.32 kDa |
| Cas No. | 677010-34-3 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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