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Motavizumab
(Synonyms: MEDI-524, MEDI524) Copy Product Info
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Synonyms: MEDI-524, MEDI524
Catalog No. T76752 Copy Product Info
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Motavizumab (MEDI-524) is a monoclonal antibody neutralizing respiratory syncytial virus (RSV), altering local and systemic cytokine responses in mouse models, used in the study of RSV infection.
Cas No. 677010-34-3
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | In Stock | In Stock | |
| 5 mg | $579 | In Stock | In Stock | |
| 10 mg | $892 | - | In Stock | |
| 25 mg | $1,350 | - | In Stock | |
| 50 mg | $1,820 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.17% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Motavizumab (MEDI-524) is a monoclonal antibody neutralizing respiratory syncytial virus (RSV), altering local and systemic cytokine responses in mouse models, used in the study of RSV infection. |
| Targets & IC50 | mIgA2:0.2976 nM(EC50), IgG1:0.07823 nM (EC50), mIgA1:0.1986 nM (EC50) |
| In vivo | In a mouse model, prophylactic administration of Motavizumab (1.25 mg/ mouse) significantly reduced respiratory syncytial virus (RSV) replication, local and systemic cytokine responses, especially TNF-α, IL-1α, IL-12p70, KC, IL-10, and INF-γ. And completely prevented the development of clinically acute RSV disease. [1] |
| Synonyms | MEDI-524, MEDI524 |
| Reactivity | Virus |
| Verified Activity | Immobilized Human RSV post-F Protein (His) at 2 μg/mL can bind Motavizumab. The EC50 is 0.004796 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | RSV-F |
| Molecular Weight | 145.32 kDa |
| Cas No. | 677010-34-3 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Motavizumab chemical structure | Motavizumab in vivo | Motavizumab molecular weight
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