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Anti-Transthyretin Antibody (1L450)
😃Good
Catalog No. TMAY-02232
Alias transthyretin, prealbumin, D17860, AI787086, AA408768
Anti-Transthyretin Antibody (1L450) is a Rabbit antibody targeting Transthyretin. Anti-Transthyretin Antibody (1L450) can be used in ELISA.
Anti-Transthyretin Antibody (1L450)
Anti-Transthyretin Antibody (1L450)
😃Good
Catalog No. TMAY-02232Alias transthyretin, prealbumin, D17860, AI787086, AA408768
Anti-Transthyretin Antibody (1L450) is a Rabbit antibody targeting Transthyretin. Anti-Transthyretin Antibody (1L450) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | transthyretin, prealbumin, D17860, AI787086, AA408768 |
| Ig Type | Rabbit IgG |
| Clone | 1L450 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Prealbumin / Transthyretin / TTR (rh Prealbumin / Transthyretin / TTR; TMPY-01756; NP_000362.1; Met 1-Glu 147). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Prealbumin/Transthyretin, also known as ATTR, Prealbumin, TTR and PALB, is a secreted and cytoplasm protein that belongs to the Prealbumin / Transthyretin family. Prealbumin / Transthyretin is detected in serum and cerebrospinal fluid (at protein level). It is highly expressed in choroid plexus epithelial cells. It is also detected in retina pigment epithelium and liver. Each monomer of Prealbumin / Transthyretin has two 4-stranded beta sheets and the shape of a prolate ellipsoid. Antiparallel beta-sheet interactions link monomers into dimers. A short loop from each monomer forms the main dimer-dimer interaction. These two pairs of loops separate the opposed, convex beta-sheets of the dimers to form an internal channel. Prealbumin/Transthyretin is a carrier protein. It transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. Defects in Prealbumin / Transthyretin are the cause of amyloidosis type 1 (AMYL1) which is a hereditary generalized amyloidosis due to Prealbumin / Transthyretin amyloid deposition. Protein fibrils can form in different tissues leading to amyloid polyneuropathies, amyloidotic cardiomyopathy, carpal tunnel syndrome, systemic senile amyloidosis. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human TTR / Prealbumin / Transthyretin protein (TMPY-01756) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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