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Anti-Mosunetuzumab Antibody (8M888)

😃Good
Catalog No. TMAS-00053
Alias RO7030816, RO 7187797, RG 7828, RG 6160, Mosunetuzumab-axgb, Lunsumio, Cevostamab, BTCT-4465A, BFCR 4350A, Anti-FCRH5/CD3 BiTE

Anti-Mosunetuzumab Antibody (8M888) is a Rabbit antibody targeting Mosunetuzumab. Anti-Mosunetuzumab Antibody (8M888) can be used in ELISA, Sandwich ELISA.

Anti-Mosunetuzumab Antibody (8M888)

Anti-Mosunetuzumab Antibody (8M888)

😃Good
Catalog No. TMAS-00053Alias RO7030816, RO 7187797, RG 7828, RG 6160, Mosunetuzumab-axgb, Lunsumio, Cevostamab, BTCT-4465A, BFCR 4350A, Anti-FCRH5/CD3 BiTE
Anti-Mosunetuzumab Antibody (8M888) is a Rabbit antibody targeting Mosunetuzumab. Anti-Mosunetuzumab Antibody (8M888) can be used in ELISA, Sandwich ELISA.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
40 μg$6097-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Mosunetuzumab Antibody (8M888) is a Rabbit antibody targeting Mosunetuzumab. Anti-Mosunetuzumab Antibody (8M888) can be used in ELISA, Sandwich ELISA.
SynonymsRO7030816, RO 7187797, RG 7828, RG 6160, Mosunetuzumab-axgb, Lunsumio, Cevostamab, BTCT-4465A, BFCR 4350A, Anti-FCRH5/CD3 BiTE
Ig Type
IgG, κ
Clone
8M888
Specificity
Mosunetuzumab and Cevostamab
Application
Recommended Dose
ELISA: 0.01-1 µg/ml; Sandwich ELISA: 0.5-2 μg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
PurificationProtein A affinity column
AppearanceLyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
FormulationLyophilized with PBS, pH 7.2, containing 0.02% sodium azide.
Research BackgroundMosunetuzumab is an innovative bispecific antibody that has a structure that resembles a natural human antibody, with two 'Fab' regions. However, it differs from naturally-occurring antibodies as one 'Fab' region targets CD20 and the other targets CD3. By recognizing and binding to these two different targets, Mosunetuzumab is able to redirect the cytotoxic activity of T-cells towards cancerous B-cells. This unique mechanism of action holds great potential for enhancing the effectiveness of cancer treatment. Cevostamab (BFCR4350A) is an innovative bispecific antibody, designed to engage T-cells and myeloma cells by targeting FcRH5 and CD3 receptors, respectively. Cevostamab possesses a unique structure with two 'Fab' regions, with one specifically targeting FcRH5 and the other targeting CD3. This dual targeting mechanism activates the patient's own T-cells and redirects them to eliminate myeloma cells expressing FcRH5 by releasing cytotoxic proteins.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Mosunetuzumab
Chemical Properties
Stability & Storage
Stability & StorageThe lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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