α-MSH acetate

Name: α-MSH acetate
Brand: TargetMol
SKU: T7813L
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7813L

Alias Lumiprobe Cy 5.5 amine, Cy 5.5 amine

α-MSH acetate is an endogenous neuromodulatory peptide derived from POMC and an agonist of MC4R (melanocortin receptor 4). It inhibits food intake, fever, and inflammation, exhibiting multiple biological activities.

α-MSH acetate

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Purity: 99.71%

Catalog No. T7813LAlias Lumiprobe Cy 5.5 amine, Cy 5.5 amine

Pack Size	Price	Availability
1 mg	$41	In Stock
5 mg	$149	In Stock
10 mg	$290	In Stock
25 mg	$622	In Stock
50 mg	$933	In Stock

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Purity:99.71%

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COA MS HPLC

Product Introduction

Bioactivity

Description	α-MSH acetate is an endogenous neuromodulatory peptide derived from POMC and an agonist of MC4R (melanocortin receptor 4). It inhibits food intake, fever, and inflammation, exhibiting multiple biological activities.
In vitro	α-MSH acetate regulates inflammation in the central nervous system (CNS) by directly acting on melanocortin receptors within glial cells; at the same time, α-MSH can modulate the activation process of NFκB and inhibit its translocation into the cell nucleus [1].
In vivo	Intraperitoneal injection of α-MSH acetate (50 μg/0.2 ml saline) effectively modulates the inflammatory response in IL-10-deficient mice. [1]
Synonyms	Lumiprobe Cy 5.5 amine, Cy 5.5 amine

Chemical Properties

Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc