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T-1228 is a highly selective inhibitor of LpxC. It effectively blocks the synthesis of LPS, leading to structural defects in the bacterial outer membrane, increased membrane permeability, and ultimately bacterial cell death. T-1228 is used in research on Gram-negative bacterial infections.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | T-1228 is a highly selective inhibitor of LpxC. It effectively blocks the synthesis of LPS, leading to structural defects in the bacterial outer membrane, increased membrane permeability, and ultimately bacterial cell death. T-1228 is used in research on Gram-negative bacterial infections. |
| Molecular Weight | 457.48 |
| Formula | C23H27N3O7 |
| Cas No. | 1884551-35-2 |
| Smiles | [C@@](N(C(=O)C1=CC=C(C#CC2=CC=C([C@@H](CO)O)C=C2)C=C1)C)(C(NC)=O)(C(NO)=O)C.O |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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