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Litorin acetate(55749-97-8 Free base)

Catalog No. T20604L

Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. It stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in vivo.

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Litorin acetate(55749-97-8 Free base), CAS N/A

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. It stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in vivo.
In vitro	99mTc-Litorin is developed for non-invasive imaging of tumors with overexpressed gastrin-releasing peptide receptors (GRP-R)[1]. [D-Phe1,Leu8,9]Litorin inhibits binding of 125I-[Tyr4] BN to murine Swiss 3T3 cells with a Ki of 5.1 nM[2]. Litorin stimulates 3H-Thymidine incorporation in murine Swiss 3T3 cells with an EC50 of 2.3 nM[2].
In vivo	Litorin stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in in vivo experiments[2].

Molecular Weight	1145.29
Formula	C53H72N14O13S

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Related Products

Related compounds with same targets

[D-Phe12]-Bombesin acetate [D-Phe12,Leu14]-Bombesin acetate BA 1 acetate(183241-31-8 free base) RC-3095 TFA Bombesin acetate(31362-50-2 free base) Kuwanon H ML-18 kuwanon G

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Litorin acetate(55749-97-8 Free base) GPCR/G Protein Bombesin Receptor Litorin acetate Inhibitor inhibitor inhibit

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