keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NF(N-Me)GA(N-Me)IL is a biologically active peptide, representing a modified segment (amino acids 22 to 27) of the human islet amyloid polypeptide (hIAPP) sequence NFGAIL. This modification includes N-methylations at G24 and I26, transforming the amyloidogenic and cytotoxic nature of the original sequence into a non-amyloidogenic and non-cytotoxic variant. Moreover, the peptide maintains the ability to bind with high affinity to full-length hIAPP, effectively inhibiting its fibril formation.
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Description | NF(N-Me)GA(N-Me)IL is a biologically active peptide, representing a modified segment (amino acids 22 to 27) of the human islet amyloid polypeptide (hIAPP) sequence NFGAIL. This modification includes N-methylations at G24 and I26, transforming the amyloidogenic and cytotoxic nature of the original sequence into a non-amyloidogenic and non-cytotoxic variant. Moreover, the peptide maintains the ability to bind with high affinity to full-length hIAPP, effectively inhibiting its fibril formation. |
Synonyms | Amylin (22-27) [NMeG24, NMeI26], human (IAPP) |
Molecular Weight | 661.79 |
Formula | C32H51N7O8 |
CAS No. | 409085-42-3 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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NF(N-Me)GA(N-Me)IL 409085-42-3 Amylin (22-27) [NMeG24, NMeI26], human (IAPP) inhibitor inhibit