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Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.

Formamide, N-(5-amino-2-((5-(1,3-dioxoisoindolin-2-yl)pentyl)oxy)benzyl)- is a bioactive chemical.

Fluphenazine is a traditional antipsychotic compound that tightly binds the dopamine D2 receptor (Ki = 0.55 nM) and also reversibly inhibits calmodulin at micromolar concentrations. Fluphenazine-N-2-chloroethane is a derivative of fluphenazine that contains an alkylating chlorethylamine chain, which produces irreversible protein binding. It is a relatively selective, irreversible antagonist of D2 receptors both in vitro (IC50 = 100 nM) and in vivo, inactivating approximately 90% of D2 receptors in mice within 4 hours of treatment. Through this action, fluphenazine-B-2-chloroethane can be used to induce catalepsy in mice. It irreversibly inhibits calmodulin at higher doses (IC50 = 10 μM), which can sensitize cancer cells to TRAIL-induced apoptosis.

N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide binds to the cannabinoid 1 (CB1) receptor with a Ki value of 365 nM in a radioligand binding assay using rat brain homogenate. It has an EC50 value of 698 nM for the peroxisome proliferator-activated receptor α (PPARα) in a luciferase reporter assay and, in rats, it decreases food intake. It does not inhibit fatty acid amide hydrolase (FAAH).

Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl) (3-methoxy-N-(3-(thiazolo[5,4-b]pyridin-2-yl)phenyl)benzamide) is a sirtuin modulator and useful for increasing the lifespan of a cell, and treating and or preventing a wide variety of diseases and disorders including diabetes, cardiovascular disease, bloo

N-(5-((4-(1-Methyl-1H-indol-3-yl)pyridin-2-yl)amino)-2-(2-methylpyrrolidin-1-yl)phenyl)acrylamide is a useful organic compound for research related to life sciences and the catalog number is T64829.

N-(5-((4-(1-Methyl-1H-indol-3-yl)pyridin-2-yl)amino)-2-(piperidin-1-yl)phenyl)acrylamide is a useful organic compound for research related to life sciences and the catalog number is T64835.

(S)-N-(1-Amino-5-guanidino-1-oxopentan-2-yl)benzamide hydrochloride, with catalog number T65350 and CAS number 4299-03-0, is a valuable organic compound used in life sciences research.

N-(1-(Dipropylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)benzamide is a useful organic compound for research related to life sciences. The catalog number is T65430 and the CAS number is 57227-09-5.

N-(4-(4-Fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T65584 and the CAS number is 147118-37-4.

N-(5-((Diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T66148 and the CAS number is 289042-10-0.

Ethyl 3-(2-(((4-cyanophenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate is a useful organic compound for research related to life sciences. The catalog number is T66212 and the CAS number is 211915-84-3.

(Z)-2,2,2-Trifluoro-N'-(piperazin-2-ylidene)acetohydrazide is a useful organic compound for research related to life sciences. The catalog number is T66623 and the CAS number is 849832-73-1.

N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)furan-2-carboxamide hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T66667.

(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid is a potential SSTR4 agonist.

N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyrazine-2-carboxamide exhibit an inhibitory effect on bacterial DNA helicases, nucleases, or helicase-nuclease enzyme complexes, such as, for example, one or more enzymes selected from the RecBCD and AddAB families of enzymes.

Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine is a PEG lipid that enhances the delivery efficiency and tissue specificity of poorly soluble drugs. It is applicable in drug delivery research.

Isotetrandrine N-2'-oxide is a natural product for research related to life sciences. The catalog number is TN4335 and the CAS number is 70191-83-2.

N-(Furan-2-ylmethyl)acetamide is a furan derivative widely used in biochemical experiments and drug synthesis research.

N-Methylbutan-2-amine is a secondary amine compound widely used in biochemical experiments and drug synthesis research.

N-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl propanamide belongs to Heterocyclic Compounds - Purine; Intermediates and Building Blocks - Nucleoside base, Electrophile; Scaffold and Template.

N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl propanamide belongs to Heterocyclic Compounds - Purine; Intermediates and Building Blocks - Nucleoside base, Electrophile; Scaffold and Template.

2-Amino-N-2-naphthalenylacetamide is a reagent used in biochemical reactions.

2-NP is a STAT1 enhancer.