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Anti-VNN2 Antibody (9J30)

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Catalog No. TMAY-02027
Alias VNN2, vanin 2, GPI-80, FOAP-4

Anti-VNN2 Antibody (9J30) is a Mouse antibody targeting VNN2. Anti-VNN2 Antibody (9J30) can be used in ELISA,ELISA(Cap),FCM.

Anti-VNN2 Antibody (9J30)

Anti-VNN2 Antibody (9J30)

😃Good
Catalog No. TMAY-02027Alias VNN2, vanin 2, GPI-80, FOAP-4
Anti-VNN2 Antibody (9J30) is a Mouse antibody targeting VNN2. Anti-VNN2 Antibody (9J30) can be used in ELISA,ELISA(Cap),FCM.
Pack SizePriceAvailabilityQuantity
20 μL$68 7-10 days
100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-VNN2 Antibody (9J30) is a Mouse antibody targeting VNN2. Anti-VNN2 Antibody (9J30) can be used in ELISA,ELISA(Cap),FCM.
AliasVNN2, vanin 2, GPI-80, FOAP-4
Ig Type
Monoclonal Mouse IgG1
Clone
9J30
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human VNN2 expression on human whole blood monocytes (left panel) and granulocytes (right panel). Cells were stained with purified anti-Human VNN2, then a FITC-conjugated second step antibody. The histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes and granulocytes.
Application
ELISA,ELISA(Cap),FCM
Recommended Dose
ELISA: 1:1000-1:2000; FCM: 1:25-1:100; ELISA(Cap): 1:250-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VNN2 / Vanin-2 (rh VNN2 / Vanin-2; TMPY-01614; NP_004656.2; Met 1-Ser 492). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundVascular non-inflammatory molecule 2, also known as glycosyl-phosphatidyl inositol-anchored protein GPI-8, Vanin-2, Protein FOAP-4 and VNN2, is a cell membrane protein that belongs to the CN hydrolase family and Vanin subfamily. VNN2 is widely expressed with higher expression in spleen and blood. VNN2 is a member of the vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. VNN2 is an amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. It is involved in the thymus homing of bone marrow cells. VNN2 plays a role in transendothelial migration of neutrophils and may regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
FITC/PE
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Human VNN2 protein (TMPY-01614)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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