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Tocainide hydrochloride

Name: Tocainide hydrochloride
Brand: TargetMol
SKU: T9234
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9234Cas No. 35891-93-1

Alias 2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride

Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker. It blocks the sodium channels in the pain-producing foci in the nerve membranes.

Tocainide hydrochloride

🥰Excellent

Purity: 97%

Catalog No. T9234Alias 2-amino-n-(2,6-dimethylphenyl)propanamide hydrochlorideCas No. 35891-93-1

Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker. It blocks the sodium channels in the pain-producing foci in the nerve membranes.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$30	In Stock	In Stock
10 mg	$48	In Stock	In Stock
25 mg	$90	In Stock	In Stock
50 mg	$139	In Stock	In Stock
100 mg	$208	In Stock	In Stock
200 mg	$321	In Stock	-
1 mL x 10 mM (in DMSO)	$32	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97%

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COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description	Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker. It blocks the sodium channels in the pain-producing foci in the nerve membranes.
In vitro	Tocainide hydrochloride effectively suppresses ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Termination of tocainide hydrochloride infusion in both digitalis toxicity and coronary occlusion models results in prompt return of ventricular ectopic activity[1].
Synonyms	2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride

Chemical Properties

Molecular Weight	228.72
Formula	C₁₁H₁₇ClN₂O
Cas No.	35891-93-1
Smiles	Cl.CC(N)C(=O)Nc1c(C)cccc1C
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (262.33 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.74 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3722 mL	21.8608 mL	43.7216 mL	218.6079 mL
5 mM	0.8744 mL	4.3722 mL	8.7443 mL	43.7216 mL
10 mM	0.4372 mL	2.1861 mL	4.3722 mL	21.8608 mL
20 mM	0.2186 mL	1.0930 mL	2.1861 mL	10.9304 mL
50 mM	0.0874 mL	0.4372 mL	0.8744 mL	4.3722 mL
100 mM	0.0437 mL	0.2186 mL	0.4372 mL	2.1861 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc