Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the study of spinal muscular atrophy (SMA).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 159.00 | |
5 mg | In stock | $ 395.00 | |
10 mg | In stock | $ 642.00 | |
25 mg | In stock | $ 993.00 | |
50 mg | In stock | $ 1,330.00 | |
100 mg | In stock | $ 1,780.00 | |
500 mg | In stock | $ 3,620.00 |
Description | SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the study of spinal muscular atrophy (SMA). |
In vitro | SMN-C2 (20 mg/kg/day) used in Δ7 mice (a severe model of SMA) can substitute SMN2 splicing, causing an increase in SMN protein levels in the brains and spinal cords of mice, improving mouse motor function, and extending mouse lifespan[1]. |
Molecular Weight | 417.5 |
Formula | C24H27N5O2 |
CAS No. | 1446311-56-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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SMN-C2 1446311-56-3 Cell Cycle/Checkpoint DNA Damage/DNA Repair DNA/RNA Synthesis inhibitor inhibit