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Anti-Dedicator of cytokinesis protein 2 Antibody (9R377) is a Rabbit antibody targeting Dedicator of cytokinesis protein 2. Anti-Dedicator of cytokinesis protein 2 Antibody (9R377) can be used in IHC, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $369 | 7-10 days | 7-10 days | |
| 100 μL | $677 | 7-10 days | 7-10 days |
| Description | Anti-Dedicator of cytokinesis protein 2 Antibody (9R377) is a Rabbit antibody targeting Dedicator of cytokinesis protein 2. Anti-Dedicator of cytokinesis protein 2 Antibody (9R377) can be used in IHC, WB. |
| Synonyms | IMD40, DOCK 2 |
| Ig Type | IgG |
| Clone | 9R377 |
| Reactivity | Human |
| Specificity | Dedicator of cytokinesis protein 2 |
| Verified Activity | Western blot analysis of DOCK2 expression in Jurkat cell lysate. |
| Application | |
| Recommended Dose | IHC: 1:100-1:200; WB: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Supplied in 10 mM phosphate buffered saline, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Research Background | Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2. |
| Conjucates | Unconjugated |
| Immunogen | A synthesized peptide: human Dedicator of cytokinesis protein 2 |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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