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Anti-Desmocollin 2/DSC2 Antibody (9S190)

🥰Excellent
Catalog No. TMAY-03794

Anti-Desmocollin 2/DSC2 Antibody (9S190) is a Mouse antibody targeting Desmocollin 2/DSC2. Anti-Desmocollin 2/DSC2 Antibody (9S190) can be used in ELISA.

Anti-Desmocollin 2/DSC2 Antibody (9S190)

Anti-Desmocollin 2/DSC2 Antibody (9S190)

🥰Excellent
Catalog No. TMAY-03794
Anti-Desmocollin 2/DSC2 Antibody (9S190) is a Mouse antibody targeting Desmocollin 2/DSC2. Anti-Desmocollin 2/DSC2 Antibody (9S190) can be used in ELISA.
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Product Introduction

Bioactivity
Description
Anti-Desmocollin 2/DSC2 Antibody (9S190) is a Mouse antibody targeting Desmocollin 2/DSC2. Anti-Desmocollin 2/DSC2 Antibody (9S190) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG1
Clone
9S190
Reactivity
Rat
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat DSC2 (TMPY-03370; Q3T1K6; Met1-Pro694).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundDSC2 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Like other desmocollins, murine DSC2 has two products, Dsc2a and Dsc2b, produced by alternative splicing of a 46 bp exon which encodes 11 COOH-terminal aa followed by an in-frame stop codon. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in DSC2 are associated with arrhythmogenic right ventricular dysplasia-11. DSC2 is Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. DSC2 may contribute to epidermal cell positioning by mediating differential adhesiveness between cells that express different isoforms.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Rat DSC2 protein (TMPY-03370)
Antigen Species
Rat
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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