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SDH-IN-28

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Catalog No. T210667

SDH-IN-28 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 2.65 mg/L. It exhibits broad-spectrum antifungal activity, showing EC50 values of 0.21 mg/L for Valsa mali, 0.95 mg/L for Botrytis cinerea, 0.64 mg/L for Botrytis cinerea, 1.33 mg/L for Rhizoctonia solani, and 0.66 mg/L for Fusarium graminearum and Gaeumannomyces gramini. SDH-IN-28 is effective in preventing V. mali from causing apple rot disease.

SDH-IN-28

SDH-IN-28

😃Good
Catalog No. T210667
SDH-IN-28 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 2.65 mg/L. It exhibits broad-spectrum antifungal activity, showing EC50 values of 0.21 mg/L for Valsa mali, 0.95 mg/L for Botrytis cinerea, 0.64 mg/L for Botrytis cinerea, 1.33 mg/L for Rhizoctonia solani, and 0.66 mg/L for Fusarium graminearum and Gaeumannomyces gramini. SDH-IN-28 is effective in preventing V. mali from causing apple rot disease.
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Product Introduction

Bioactivity
Description
SDH-IN-28 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 2.65 mg/L. It exhibits broad-spectrum antifungal activity, showing EC50 values of 0.21 mg/L for Valsa mali, 0.95 mg/L for Botrytis cinerea, 0.64 mg/L for Botrytis cinerea, 1.33 mg/L for Rhizoctonia solani, and 0.66 mg/L for Fusarium graminearum and Gaeumannomyces gramini. SDH-IN-28 is effective in preventing V. mali from causing apple rot disease.
In vitro
SDH-IN-28 (Compound 4d) exhibits significant fungicidal activity at a concentration of 20 mg/L, achieving inhibition rates of 100%, 94.3%, 86.1%, 100%, 88.0%, 100%, and 66.1% against V. mali, S. sclerotiorum, B. cinerea, R. solani, F. graminearum, G. graminis, and P. capsici, respectively. Additionally, SDH-IN-28 (50 mg/L, 1–10 days) demonstrates effective therapeutic and protective effects in apples treated with V. mali for 24 hours.
Chemical Properties
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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