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SARS-CoV-2 Mpro-IN-21 (compound A8) is an effective inhibitor of the SARS-CoV-2 and COVID-19 Main Protease MPro. It demonstrates significant antioxidant activity in the DPPH assay with an IC50 of 0.36 mg/mL. SARS-CoV-2 Mpro-IN-21 also shows notable antibacterial activity against Klebsiella, with an IC50 of 1.19 mg/mL.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | SARS-CoV-2 Mpro-IN-21 (compound A8) is an effective inhibitor of the SARS-CoV-2 and COVID-19 Main Protease MPro. It demonstrates significant antioxidant activity in the DPPH assay with an IC50 of 0.36 mg/mL. SARS-CoV-2 Mpro-IN-21 also shows notable antibacterial activity against Klebsiella, with an IC50 of 1.19 mg/mL. |
| Molecular Weight | 331.43 |
| Formula | C17H21N3O2S |
| Cas No. | 3041099-79-7 |
| Smiles | O=C1C(=CNCCC=2C=CC=CC2)C(=O)N(C(=S)N1CC)CC |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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