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Anti-LMAN2 Antibody (5D538)
😃Good
Catalog No. TMAY-02355
Alias VIP36, lectin, mannose binding 2, GP36B, C5orf8
Anti-LMAN2 Antibody (5D538) is a Mouse antibody targeting LMAN2. Anti-LMAN2 Antibody (5D538) can be used in ELISA(Cap).
Anti-LMAN2 Antibody (5D538)
Anti-LMAN2 Antibody (5D538)
😃Good
Catalog No. TMAY-02355Alias VIP36, lectin, mannose binding 2, GP36B, C5orf8
Anti-LMAN2 Antibody (5D538) is a Mouse antibody targeting LMAN2. Anti-LMAN2 Antibody (5D538) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA(Cap) Reactivity: Human |
| Alias | VIP36, lectin, mannose binding 2, GP36B, C5orf8 |
| Ig Type | Mouse IgG2b |
| Clone | 5D538 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LMAN2 (rh LMAN2; TMPY-02419; Q12907; Asp45-Arg322). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | LMAN2 (Lectin, Mannose Binding 2, also known as VIP36) is a Protein Coding gene. This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus, and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking, and quality control. The L-type lectin LMAN2 appears to be specifically required for the accumulation of GPRC5B in the Golgi complex and restriction of GPRC5B transport along the exosomal pathway. This may occur due to interference with the adaptor protein GGA1-mediated trans-Golgi network-to-endosome transport of GPRC5B. A Golgi-traversing pathway for the exosomal release of the cargo protein GPRC5B in which CD2AP facilitates the entry and LMAN2 impedes the exit of the flux, respectively. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human LMAN2 Protein (TMPY-02419) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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