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Anti-LMAN2 Antibody (5D538)

😃Good
Catalog No. TMAY-02355
Alias VIP36, lectin, mannose binding 2, GP36B, C5orf8

Anti-LMAN2 Antibody (5D538) is a Mouse antibody targeting LMAN2. Anti-LMAN2 Antibody (5D538) can be used in ELISA(Cap).

Anti-LMAN2 Antibody (5D538)

Anti-LMAN2 Antibody (5D538)

😃Good
Catalog No. TMAY-02355Alias VIP36, lectin, mannose binding 2, GP36B, C5orf8
Anti-LMAN2 Antibody (5D538) is a Mouse antibody targeting LMAN2. Anti-LMAN2 Antibody (5D538) can be used in ELISA(Cap).
Pack SizePriceAvailabilityQuantity
20 μL$69 7-10 days
100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-LMAN2 Antibody (5D538) is a Mouse antibody targeting LMAN2. Anti-LMAN2 Antibody (5D538) can be used in ELISA(Cap).
AliasVIP36, lectin, mannose binding 2, GP36B, C5orf8
Ig Type
Monoclonal Mouse IgG2b
Clone
5D538
Reactivity
Human
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LMAN2 (rh LMAN2; TMPY-02419; Q12907; Asp45-Arg322). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundLMAN2 (Lectin, Mannose Binding 2, also known as VIP36) is a Protein Coding gene. This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus, and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking, and quality control. The L-type lectin LMAN2 appears to be specifically required for the accumulation of GPRC5B in the Golgi complex and restriction of GPRC5B transport along the exosomal pathway. This may occur due to interference with the adaptor protein GGA1-mediated trans-Golgi network-to-endosome transport of GPRC5B. A Golgi-traversing pathway for the exosomal release of the cargo protein GPRC5B in which CD2AP facilitates the entry and LMAN2 impedes the exit of the flux, respectively.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human LMAN2 Protein (TMPY-02419)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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