Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact UsQuotation
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

Cdc7-IN-20

🥰Excellent
Catalog No. T209269

Cdc7-IN-20 (EP-05) is an orally bioavailable and selective inhibitor of Cdc7, with IC50 and Ki values of 0.93 nM and 0.11 nM, respectively. It exhibits antitumor activity.

Cdc7-IN-20

Cdc7-IN-20

🥰Excellent
Catalog No. T209269
Cdc7-IN-20 (EP-05) is an orally bioavailable and selective inhibitor of Cdc7, with IC50 and Ki values of 0.93 nM and 0.11 nM, respectively. It exhibits antitumor activity.
TargetMol
Product information is being updated, if you want to purchase, please click the bulk custom button.
Bulk & Custom
Questions
View More

Resource Download

Product Introduction

Bioactivity
Description
Cdc7-IN-20 (EP-05) is an orally bioavailable and selective inhibitor of Cdc7, with IC50 and Ki values of 0.93 nM and 0.11 nM, respectively. It exhibits antitumor activity.
In vitro
Cdc7-IN-20 at concentrations of 0.5, 1, and 2 μM for 24 hours can inhibit the proliferation of COLO 205 cells.
In vivo
Cdc7-IN-20, administered orally at doses of 2, 4, and 8 mg/kg for 3 consecutive days, demonstrates antitumor activity in a COLO 205 xenograft mouse model.
Chemical Properties
FormulaC15H16N4OS
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Cdc7-IN-20 | purchase Cdc7-IN-20 | Cdc7-IN-20 cost | order Cdc7-IN-20 | Cdc7-IN-20 in vivo | Cdc7-IN-20 in vitro | Cdc7-IN-20 formula
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.