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Anti-ASAH2 Antibody (7A31) is a Rabbit antibody targeting ASAH2. Anti-ASAH2 Antibody (7A31) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $270 | 7-10 days |
Description | Anti-ASAH2 Antibody (7A31) is a Rabbit antibody targeting ASAH2. Anti-ASAH2 Antibody (7A31) can be used in ELISA. |
Alias | N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2, AI585898 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 7A31 |
Reactivity | Mouse |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse ASAH2 (rM ASAH2; TMPY-00963; Thr 34-Thr 756; NP_061300.1). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | ASAH2 (N-acylsphingosine amidohydrolase 2), also known as neutral ceramidase, is a type II integral membrane protein that can be cleaved to produce a soluble secreted protein. The enzyme is abundant in the brush border membranes of the intestine, and also expressed in several tissues such as kidney, brain and liver. The primary structure of ASAH2/neutral ceramidase is highly conserved from bacteria to humans, however, there is a clear difference in the molecular architecture. The murine ASAH2 possesses ‘amucin box’, a Ser/Thr/Pro-rich domain glycosylated with O-glycans which is necessary to retain the enzyme on the plasma membrane as a type II integral protein. The major physiological function of ASAH2/neutral ceramidase is the metabolism of dietary sphingolipids, and thus plays a role in the generation of messenger molecules such as sphingosine and sphingosine 1-phosphate. |
Conjucates | Unconjugated |
Immunogen | Recombinant Mouse ASAH2 protein (TMPY-00963) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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