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Anti-HE4 Antibody (3J765)
😃Good
Catalog No. TMAY-02394
Alias WAP four-disulfide core domain 2
Anti-HE4 Antibody (3J765) is a Mouse antibody targeting HE4. Anti-HE4 Antibody (3J765) can be used in ELISA(Cap).
Anti-HE4 Antibody (3J765)
Anti-HE4 Antibody (3J765)
😃Good
Catalog No. TMAY-02394Alias WAP four-disulfide core domain 2
Anti-HE4 Antibody (3J765) is a Mouse antibody targeting HE4. Anti-HE4 Antibody (3J765) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $68 | 7-10 days | |
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-HE4 Antibody (3J765) is a Mouse antibody targeting HE4. Anti-HE4 Antibody (3J765) can be used in ELISA(Cap). |
| Alias | WAP four-disulfide core domain 2 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 3J765 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human HE4/WFDC2/WAP5 (rh HE4/WFDC2/WAP5; TMPY-01882; NP_006094.3; Met1-Phe124). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP domains. WFDC2 / HE4 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. It is highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. WFDC2 may be a component of the innate immune defences of the lung, nasal and oral cavities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence. WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail. Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy, reduced in early lactation and absent in mid-late lactation. WFDC2 / HE4 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human HE4/WFDC2/WAP5 Protein (TMPY-01882) |
| Antigen Species | Human |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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