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Anti-VNN2 Antibody (4J489)
😃Good
Catalog No. TMAY-02028
Alias VNN2, vanin 2, GPI-80, FOAP-4
Anti-VNN2 Antibody (4J489) is a Rabbit antibody targeting VNN2. Anti-VNN2 Antibody (4J489) can be used in ELISA.
Anti-VNN2 Antibody (4J489)
Anti-VNN2 Antibody (4J489)
😃Good
Catalog No. TMAY-02028Alias VNN2, vanin 2, GPI-80, FOAP-4
Anti-VNN2 Antibody (4J489) is a Rabbit antibody targeting VNN2. Anti-VNN2 Antibody (4J489) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | VNN2, vanin 2, GPI-80, FOAP-4 |
| Ig Type | Rabbit IgG |
| Clone | 4J489 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human VNN2 / Vanin-2 (rh VNN2 / Vanin-2; TMPY-01614; NP_004656.2; Met 1-Ser 492). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Vascular non-inflammatory molecule 2, also known as glycosyl-phosphatidyl inositol-anchored protein GPI-8, Vanin-2, Protein FOAP-4 and VNN2, is a cell membrane protein that belongs to the CN hydrolase family and Vanin subfamily. VNN2 is widely expressed with higher expression in spleen and blood. VNN2 is a member of the vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. VNN2 is an amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. It is involved in the thymus homing of bone marrow cells. VNN2 plays a role in transendothelial migration of neutrophils and may regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human VNN2 / Vanin-2 protein (TMPY-01614) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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