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CRBN ligand-9

Name: CRBN ligand-9
Brand: TargetMol
SKU: T9360
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9360Cas No. 55003-81-1

Alias 2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione

CRBN ligand-9 (2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione) exhibit inhibition of CRBN.

CRBN ligand-9

🥰Excellent

Purity: 99.88%

Catalog No. T9360Alias 2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dioneCas No. 55003-81-1

CRBN ligand-9 (2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione) exhibit inhibition of CRBN.

Pack Size	Price	Availability	Quantity
50 mg	$29	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.88%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	CRBN ligand-9 (2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione) exhibit inhibition of CRBN.
Synonyms	2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione

Chemical Properties

Molecular Weight	303.23
Formula	C₁₃H₉N₃O₆
Cas No.	55003-81-1
Smiles	O=C1N(C(=O)C=2C1=CC(N(=O)=O)=CC2)C3C(=O)NC(=O)CC3
Relative Density.	1.651 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (214.36 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2978 mL	16.4891 mL	32.9783 mL	164.8913 mL
5 mM	0.6596 mL	3.2978 mL	6.5957 mL	32.9783 mL
10 mM	0.3298 mL	1.6489 mL	3.2978 mL	16.4891 mL
20 mM	0.1649 mL	0.8245 mL	1.6489 mL	8.2446 mL
50 mM	0.0660 mL	0.3298 mL	0.6596 mL	3.2978 mL
100 mM	0.0330 mL	0.1649 mL	0.3298 mL	1.6489 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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