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(R)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one

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Catalog No. T4828Cas No. 599-04-2
Alias D-(-)-Pantolactone

Pantolactone belongs to the class of organic compounds known as gamma-butyrolactones. gamma-Butyrolactones are compounds containing a gamma-butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and bears a ketone group on the carbon adjacent to the oxygen atom.

(R)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one

(R)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one

😃Good
Purity: 99.41%
Catalog No. T4828Alias D-(-)-PantolactoneCas No. 599-04-2
Pantolactone belongs to the class of organic compounds known as gamma-butyrolactones. gamma-Butyrolactones are compounds containing a gamma-butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and bears a ketone group on the carbon adjacent to the oxygen atom.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$29-In Stock
1 mL x 10 mM (in DMSO)$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly
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Batch Information

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Purity:99.41%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Pantolactone belongs to the class of organic compounds known as gamma-butyrolactones. gamma-Butyrolactones are compounds containing a gamma-butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and bears a ketone group on the carbon adjacent to the oxygen atom.
SynonymsD-(-)-Pantolactone
Chemical Properties
Molecular Weight130.14
FormulaC6H10O3
Cas No.599-04-2
SmilesCC1(C)COC(=O)[C@@H]1O
Relative Density.1.165g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 199.8 mM, Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 1 mg/mL (7.68 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.6840 mL38.4202 mL76.8403 mL384.2016 mL
5 mM1.5368 mL7.6840 mL15.3681 mL76.8403 mL
10 mM0.7684 mL3.8420 mL7.6840 mL38.4202 mL
20 mM0.3842 mL1.9210 mL3.8420 mL19.2101 mL
50 mM0.1537 mL0.7684 mL1.5368 mL7.6840 mL
100 mM0.0768 mL0.3842 mL0.7684 mL3.8420 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

InhibitorinhibitEndogenousMetaboliteEndogenous Metabolite(R)3Hydroxy4,4dimethyldihydrofuran2(3H)one(R) 3 Hydroxy 4,4 dimethyldihydrofuran 2(3H) one
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